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Menopause. 2016 May;23(5):488-93. doi: 10.1097/GME.0000000000000575.

Sedentary lifestyle in middle-aged women is associated with severe menopausal symptoms and obesity.

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1Universidad de Chile, Santiago de Chile, Chile 2Clínica AVANSALUD, Santiago de Chile, Chile 3Universidad Católica de Santiago de Guayaquil, Hospital Enrique C. Sotomayor, Guayaquil, Ecuador 4Instituto Nacional de Salud, Lima, Perú 5Universidad Nacional de Cuyo, Mendoza, Argentina 6Hospital de Clínicas, Buenos Aires, Argentina 7Universidad de Panamá, Panamá 8Clínica SOLCA, Machala, Ecuador 9Universidad de Ciencias Aplicadas y Ambientales, Bogotá, Colombia 10Universidad Andina del Cusco, Cusco, Perú 11UDIME, Santa Cruz de la Sierra, Bolivia 12Universidad de Cartagena, Cartagena de Indias, Colombia 13Facultad de Medicina CLAEH, Punta del Este, Uruguay 14Universidad Nacional de Rosario, Rosario, Argentina 15Atención Médica Integral para la Mujer, Naucalpan, México 16Universidad del Valle, Cali, Colombia 17Instituto de Endocrinología, Cochabamba, Bolivia 18Universidad Diego Portales, Santiago, Chile 19Universidad Central del Ecuador, Quito, Ecuador 20Universidad de Guadalajara, Gaudalajara, México 21Universidad Nacional de Asunción, Asunción, Paraguay 22Hospital Metropolitano de Santiago, Santiago de los Caballeros, República Dominicana 23Universidad El Bosque, Bogotá, Colombia.



The aim of the study was to evaluate the association between sedentary lifestyle and the severity of menopausal symptoms and obesity in middle-aged women.


The Menopause Rating Scale, the Goldberg Anxiety and Depression Scale, and the Athens Insomnia Scale were administered to 6,079 Latin American women aged 40 to 59 years. Sedentary lifestyle was defined as fewer than three weekly, 30-minute periods of physical activity.


Sedentary women had more severe menopausal symptoms (total Menopause Rating Scale score: 9.57 ± 6.71 vs 8.01 ± 6.27 points, P < 0.0001) and more depressive symptoms (Goldberg), anxiety (Goldberg), and insomnia (Athens Scale) compared with non-sedentary women. They also had greater mean waist circumference (86.2 ± 12.3 vs 84.3 ± 1.8 cm, P < 0.0001) and a higher prevalence of obesity (20.9% vs 14.3%, P < 0.0001). Logistic regression analysis showed that both obesity (odds ratio [OR] 1.52; 95% CI, 1.32-1.76) and severe menopausal symptoms (OR 1.28; 95% CI, 1.06-1.53), including insomnia and depressive mood, were positively associated with a sedentary lifestyle. Having a stable partner (OR 0.85; 95% CI, 0.76-0.96), using hormone therapy (OR 0.75; 95% CI, 0.64-0.87) and having a higher educational level (OR 0.66; 95% CI, 0.60-0.74) were negatively related to sedentary lifestyle.


There was a high prevalence of sedentary lifestyle in this middle-aged Latin American female sample which was associated with more severe menopausal symptoms and obesity.

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