What is changing in radiotherapy for the treatment of locally advanced nonsmall cell lung cancer patients? A review

Cancer Invest. 2016;34(2):80-93. doi: 10.3109/07357907.2015.1114121. Epub 2016 Jan 25.

Abstract

Radiotherapy treatment continues to have a relevant impact in the treatment of nonsmall cell cancer (NSCLC). Use of concurrent chemotherapy and radiotherapy is considered the gold standard in the treatment of locally advanced NSCLC but clinical outcomes are not satisfactory. Introduction of new radiotherapy technology and chemotherapy regimens are under investigation in this setting with the goal to improve unsatisfactory results. We report how radiotherapy is changing in the treatment of locally advanced NSCLC.

Keywords: Altered fractionation; Dose escalation; Locally advanced; New technology; Non small cell lung cancer; Radiotherapy.

Publication types

  • Review

MeSH terms

  • Carcinoma, Non-Small-Cell Lung / mortality
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Carcinoma, Non-Small-Cell Lung / radiotherapy*
  • Chemoradiotherapy / trends*
  • Diffusion of Innovation
  • Forecasting
  • Humans
  • Lung Neoplasms / mortality
  • Lung Neoplasms / pathology
  • Lung Neoplasms / radiotherapy*
  • Radiation Dosage*
  • Radiotherapy / trends
  • Treatment Outcome