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Trends Parasitol. 2016 Mar;32(3):174-176. doi: 10.1016/j.pt.2016.01.002. Epub 2016 Jan 19.

Genetic Control Of Malaria Mosquitoes.

Author information

1
Johns Hopkins Bloomberg School of Public Health, Department of Molecular Microbiology and Immunology, Malaria Research Institute, Baltimore, MD 21205, USA.
2
Johns Hopkins Bloomberg School of Public Health, Department of Molecular Microbiology and Immunology, Malaria Research Institute, Baltimore, MD 21205, USA. Electronic address: mlorena@jhsph.edu.

Abstract

Experiments demonstrating the feasibility of genetically modifying mosquito vectors to impair their ability to transmit the malaria parasite have been known for well over a decade. However, means to spread resistance or population control genes into wild mosquito populations remains an unsolved challenge. Two recent reports give hope that CRISPR technology may allow such challenge to be overcome.

PMID:
26809567
PMCID:
PMC5127165
DOI:
10.1016/j.pt.2016.01.002
[Indexed for MEDLINE]
Free PMC Article

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