Format

Send to

Choose Destination
Ocul Immunol Inflamm. 2016 Aug;24(4):397-401. doi: 10.3109/09273948.2015.1088041. Epub 2016 Jan 25.

Changes in Inflammatory Activity after Glaucoma Filtration Surgery in Children with Chronic Anterior Uveitis.

Author information

1
a Department of Ophthalmology , St. Franziskus-Hospital Muenster , Germany.
2
b Department of Ophthalmology at University of Duisburg-Essen , Germany.

Abstract

PURPOSE:

To evaluate changes in inflammatory activity over time in patients with juvenile idiopathic arthritis (JIA)-associated anterior uveitis after two different types of glaucoma surgery.

METHODS:

Retrospective analysis of 32 patients with JIA who had trabeculectomy (TE, 21 eyes) or Ahmed glaucoma valve implantation (AGV, 11 eyes). Inflammatory activity and use of anti-inflammatory medication were evaluated 1 year prior to surgery and in the first, third, and fifth years after surgery.

RESULTS:

In both groups IOP decreased significantly from pre-surgery to 2 years after surgery (TE, 31.1 ± 6.7 to 12.8 ± 6.1 mmHg, p<0.0001; AGV, 28.5 ± 8.5 to 14.9 ± 6.6 mmHg, p<0.001). In the TE group flare, anterior chamber cells, and uveitis activity decreased significantly after surgery, whereas with AGV there was no sustained reduction of flare.

CONCLUSIONS:

The degree of inflammation in JIA-associated uveitis is significantly reduced after trabeculectomy.

KEYWORDS:

Uveitis; glaucoma; inflammation; trabeculectomy

PMID:
26808003
DOI:
10.3109/09273948.2015.1088041
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center