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Scand J Public Health. 2016 Jun;44(4):402-10. doi: 10.1177/1403494815622859. Epub 2016 Jan 19.

East-west differences and migration in Finland: Association with cardiometabolic risk markers and IMT. The Cardiovascular Risk in Young Finns Study.

Author information

1
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland lauri.vahamurto@utu.fi.
2
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland Paavo Nurmi Centre, Sports and Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland.
3
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia.
4
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland Department of Food and Environmental Sciences, University of Helsinki, Finland.
5
Department of Pediatrics, University of Tampere and Tampere University Hospital, Tampere, Finland.
6
Department of Clinical Physiology, Tampere University Hospital and University of Tampere, Tampere, Finland.
7
Department of Clinical Physiology and Nuclear Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
8
Vaasa Central Hospital, Vaasa, Finland.
9
Department of Pediatrics, University of Oulu, Oulu, Finland.
10
Fimlab Laboratories and Department of Clinical Chemistry, School of Medicine, University of Tampere, Tampere, Finland.
11
Department of Pediatric Cardiology, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland.
12
LIKES-Research Center for Sport and Health Sciences, Jyväskylä, Finland.
13
Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland.
14
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland.
15
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.

Abstract

BACKGROUND:

Coronary heart disease mortality has been internationally high in eastern Finland. The excessive mortality risk in Eastern compared with western Finns is explained by differences in cardiometabolic risk profile. Current risk profile differences and association with migration have not been reported. We examined the association of place of residence (east-west) and specifically migration with cardiometabolic risk markers and carotid intima-media thickness (IMT).

METHODS:

The study population included 2204 participants with data available from childhood/youth in 1980 and follow-up examination in 2007.

RESULTS:

Participants residing in eastern Finland in adulthood had 0.022±0.004mm higher IMT than Western participants. Those who migrated east-to-west had lower IMT than those staying in the east (0.027±0.006mm, p<0.0001) while no difference to those continuously living in the west was found. Those who moved east-to-west had a lower body mass index (25.3±4.3 kg/m(2) vs. 26.2±4.5kg/m(2), p=0.01), waist circumference (85.7±12.8cm vs. 88.6±12.8cm, p=0.001), prevalence of metabolic syndrome (13% vs. 21%, p=0.01), and higher socioeconomic status (16.6±3.3 vs. 15.0±3.3 school years, p<0.0001) than those who stayed in the east. CONCLUSIONS HIGHER IMT WAS FOUND IN EASTERN FINNS THAN IN WESTERN FINNS PARTICIPANTS WHO MIGRATED EAST-TO-WEST HAD A LOWER IMT AND A BETTER CARDIOMETABOLIC RISK PROFILE THAN THOSE WHO STAYED IN THE EAST.

KEYWORDS:

Atherosclerosis; endothelium; human migration; risk factors; vascular

PMID:
26787555
DOI:
10.1177/1403494815622859
[Indexed for MEDLINE]

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