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Ann Ist Super Sanita. 2015;51(4):327-35. doi: 10.4415/ANN_15_04_13.

A cost-consequence analysis of hepatitis B screening in an immigrant population.

Author information

1
Dipartimento di Medicina Molecolare, Università degli Studi di Padova, Padua, Italy.
2
Dipartimento di Gastroenterologia, ASL 16 Ospedale Generale, Regione Veneto, Padua, Italy.
3
Pharmacist, freelance economic consultant.
4
Clinical Research and Innovation Direction, Léon Bérard Cancer Centre, Lyon, France.

Abstract

OBJECTIVE:

Screening for HBV among groups at risk, such as migrant populations, has proved to be a cost-effective strategy. With a view to advising local policy-makers, the cost-consequences of HBV screening was assessed using a modeling approach.

METHODS:

This cost-consequence analysis of an HBV screening strategy was conducted in a cohort of adult migrants in the province of Padua, northern Italy.

RESULTS:

The population targeted for screening consisted of 65 405 migrants, among whom the weighted rate for the prevalence of HBV was 0.04972, with 3251 people infected. Over a period of 5 years, the screening strategy prevented 565 cases/year of chronic hepatitis, 141 of compensated cirrhosis, 9 of decompensated cirrhosis, 14 hepatocellular carcinomas and 12 deaths. The above data revealed that the incremental cost of the screening strategy compared to no screening strategy was € 7 974 959 over the five year period. The cost per life saved amounted to € 676 709.

CONCLUSIONS:

The present study provides useful information to policy-makers at local and regional levels.

PMID:
26783220
DOI:
10.4415/ANN_15_04_13
[Indexed for MEDLINE]
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