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Probiotics Antimicrob Proteins. 2009 Dec;1(2):143. doi: 10.1007/s12602-009-9020-0.

Natural Antimicrobials ε-Poly-L-lysine and Nisin A for Control of Oral Microflora.

Author information

1
Department of Food Science, Rutgers, The State University of New Jersey, 65 Dudley Road, New Brunswick, NJ, 08901, USA.
2
Department of Food Science, Rutgers, The State University of New Jersey, 65 Dudley Road, New Brunswick, NJ, 08901, USA. tchikindas@aesop.rutgers.edu.

Abstract

The present study aims to examine the efficacy of the natural antimicrobial ε-poly-L-lysine against Streptococcus mutans and against total aerobic oral microflora, alone and in combination with the natural antimicrobial peptide nisin. In in vitro studies, natural antimicrobials nisin A and ε-poly-L-lysine synergized in their action against S. mutans, leading to the microorganism's full inhibition, while having a less inhibitory effect on total aerobic oral microbiota.

KEYWORDS:

Antimicrobial; Nisin; Oral microflora; Poly-lysine; Synergy

PMID:
26783169
DOI:
10.1007/s12602-009-9020-0

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