Format

Send to

Choose Destination
Genome Biol Evol. 2016 Jan 18;8(2):317-29. doi: 10.1093/gbe/evv263.

Evidence of Natural Hybridization in Brazilian Wild Lineages of Saccharomyces cerevisiae.

Author information

1
UCIBIO-REQUIMTE, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Caparica, Portugal.
2
Departamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
3
Laboratório de Microbiologia Ambiental e Biotecnologia, Universidade Federal de Tocantins, Palmas, TO, Brazil.
4
Département de Biologie, Institut de Biologie Intégrative et Des Systèmes (IBIS), Université Laval, Pavillon Charles-Eugènes-Marchand, QC, Canada.
5
Département des Sciences Biologiques, Pavillon Marie-Victorin, 90 Rue Vincent D'indy-Université de Montréal, Montréal, QC, Canada.
6
UCIBIO-REQUIMTE, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Caparica, Portugal jss@fct.unl.pt.

Abstract

The natural biology of Saccharomyces cerevisiae, the best known unicellular model eukaryote, remains poorly documented and understood although recent progress has started to change this situation. Studies carried out recently in the Northern Hemisphere revealed the existence of wild populations associated with oak trees in North America, Asia, and in the Mediterranean region. However, in spite of these advances, the global distribution of natural populations of S. cerevisiae, especially in regions were oaks and other members of the Fagaceae are absent, is not well understood. Here we investigate the occurrence of S. cerevisiae in Brazil, a tropical region where oaks and other Fagaceae are absent. We report a candidate natural habitat of S. cerevisiae in South America and, using whole-genome data, we uncover new lineages that appear to have as closest relatives the wild populations found in North America and Japan. A population structure analysis revealed the penetration of the wine genotype into the wild Brazilian population, a first observation of the impact of domesticated microbe lineages on the genetic structure of wild populations. Unexpectedly, the Brazilian population shows conspicuous evidence of hybridization with an American population of Saccharomyces paradoxus. Introgressions from S. paradoxus were significantly enriched in genes encoding secondary active transmembrane transporters. We hypothesize that hybridization in tropical wild lineages may have facilitated the habitat transition accompanying the colonization of the tropical ecosystem.

KEYWORDS:

Saccharomyces paradoxus; genome evolution; introgression; microbe population genomics; yeast molecular ecology

PMID:
26782936
PMCID:
PMC4779607
DOI:
10.1093/gbe/evv263
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center