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Br J Dermatol. 2016 Feb;174(2):287-95. doi: 10.1111/bjd.14337. Epub 2016 Jan 18.

Report from the kick-off meeting of the Cochrane Skin Group Core Outcome Set Initiative (CSG-COUSIN).

Author information

1
Centre for Evidence-Based Healthcare, Medizinische Fakultät Carl Gustav Carus, TU Dresden, Dresden, Germany.
2
Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, U.K.
3
Department of Dermatology, Northwestern University, Chicago, IL, U.S.A.
4
Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
5
Department for Development, Research and Health Technology Assessment, Agency for Quality and Accreditation in Health Care and Social Welfare, Zagreb, Croatia.
6
Department of Dermatology, University Hospital Carl Gustav Carus, Dresden, Germany.
7
Department of Dermatology, AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, France.
8
Université Paris-Est Créteil, Créteil, France.
9
Satellite Français du Cochrane Skin Group, France.
10
EA EpiDermE, INSERM Créteil, Créteil, France.
11
Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, U.K.
12
Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
13
German Center for Health Services Research in Dermatology (CVderm), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
14
Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
15
IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
16
Universitat Pompeu Fabra (UPF), Barcelona, Spain.
17
CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
18
VU University Medical Center, Department of Epidemiology and Biostatistics, the EMGO Institute for Health and Care Research, Amsterdam, the Netherlands.
19
Derby Teaching Hospitals NHS Foundation Trust, Derby, U.K.
20
Department of Dermatology, Venereology, and Allergology, J.W. Goethe-University, Hospital, Frankfurt, Germany.
21
Evidence-Based Medicine Frankfurt, Institute for General Practice, Goethe-University, Frankfurt, Germany.
22
Department of Dermatology, Venerology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany.
23
Department of Dermatology, Venerology and Allergy, Division of Evidence Based Medicine (dEBM), Charité - Universitätsmedizin Berlin, Berlin, Germany.
24
Centre of Wound Healing, Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Dessau, Germany.

Abstract

A major obstacle of evidence-based clinical decision making is the use of nonstandardized, partly untested outcome measurement instruments. Core Outcome Sets (COSs) are currently developed in different medical fields to standardize and improve the selection of outcomes and outcome measurement instruments in clinical trials, in order to pool results of trials or to allow indirect comparison between interventions. A COS is an agreed minimum set of outcomes that should be measured and reported in all clinical trials of a specific disease or trial population. The international, multidisciplinary Cochrane Skin Group Core Outcome Set Initiative (CSG-COUSIN) aims to develop and implement COSs in dermatology, thus making trial evidence comparable and, herewith, more useful for clinical decision making. The inaugural meeting of CSG-COUSIN was held on 17-18 March 2015 in Dresden, Germany, as the exclusive theme of the Annual Cochrane Skin Group Meeting. In total, 29 individuals representing a broad mix of different stakeholder groups, professions, skills and perspectives attended. This report provides a description of existing COS initiatives in dermatology, highlights current methodological challenges in COS development, and presents the concept, aims and structure of CSG-COUSIN.

PMID:
26779929
DOI:
10.1111/bjd.14337
[Indexed for MEDLINE]

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