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J Vet Cardiol. 2015 Dec;17 Suppl 1:S134-49. doi: 10.1016/j.jvc.2015.07.003.

Screening for hypertrophic cardiomyopathy in cats.

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Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Box 7054, Uppsala, Sweden. Electronic address:
The Royal Veterinary College, Department of Clinical Science and Services, Hawkshead Lane, Hatfield AL9 7TA, United Kingdom.
Clinic of Small Animal Medicine, LMU University, Veterinaerstr. 13, 80539 Munich, Germany.


Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats, and it can lead to increased morbidity and mortality. Cats are often screened for HCM because of the presence of a heart murmur, but screening for breeding purposes has also become common. These cats are usually purebred cats of breeding age, and generally do not present with severe disease or with any clinical signs. This type of screening is particularly challenging because mild disease may be difficult to differentiate from a normal phenotype, and the margin for error is small, with potentially major consequences for the breeder. This article reviews HCM screening methods, with particular emphasis on echocardiography.


Biomarkers; Breeding programs; Echocardiography; Genetic background

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