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Trends Neurosci. 2016 Feb;39(2):51-53. doi: 10.1016/j.tins.2015.12.010. Epub 2016 Jan 6.

Fight, Flight, or Freeze? The Answer May Depend on Your Sex.

Author information

1
Department of Psychology, University of Texas at Austin, 1 University Station, A8000 Austin, TX 78712, USA.
2
Department of Psychology, University of Texas at Austin, 1 University Station, A8000 Austin, TX 78712, USA. Electronic address: marie.monfils@utexas.edu.

Abstract

Pavlovian fear conditioning is one of the most common and well-understood methods for studying fear learning. However, research is predominantly performed in males. Recently, in a classical Pavlovian fear conditioning paradigm, Gruene and colleagues described an active conditioned fear response ('darting') prevalent in female rats that better maintain an extinction memory.

KEYWORDS:

escape; fear conditioning; females; sex differences

PMID:
26776563
DOI:
10.1016/j.tins.2015.12.010
[Indexed for MEDLINE]

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