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Clin Oral Implants Res. 2017 Jan;28(1):109-115. doi: 10.1111/clr.12768. Epub 2016 Jan 16.

Development of Implant Stability Quotient values of implants placed with simultaneous sinus floor elevation - results of a prospective study with 109 implants.

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Department of Oral Surgery and Stomatology, University of Bern, Bern, Switzerland.
Department of Oral Surgery, Medical University of Vienna, Vienna, Austria.
Department of Reconstructive Dental Medicine and Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Laboratory of Oral Cell Biology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Department of Oral Biology, Medical University of Vienna, Vienna, Austria.



In patients with implant placement and simultaneous sinus floor elevation (SFE), healing periods of 6 months have been the standard of care for more than 25 years. The primary objective of this prospective case series study was to determine what percentage of implants placed with SFE reach a threshold Implant Stability Quotient (ISQ) of ≥70 after 8 weeks of healing using Resonance Frequency Analysis (RFA).


A total of 109 dental implants were placed in 97 patients. SFE was carried out with a lateral window approach and a mixture of autogenous bone chips and deproteinized bovine bone mineral (DBBM). Titanium screw-type, tissue-level implants with a chemically modified SLA surface were used. ISQ values were measured after implant insertion (ISQBL ) and after 8 weeks of healing (ISQ8 wk ). Patients showing ISQ8 wk  ≥ 70 subsequently underwent restoration. Implants with an ISQ value < 70 were recalled at 2-week intervals.


The ISQ at baseline had a mean value of 68.3 (SD ± 9.8). At 8 weeks, the mean ISQ value was 73.6 (SD ± 6.4). This increase was statistically significant (P < 0.001). An ISQ8 wk value ≥70 was observed for 91 implants (83%). One implant (0.9%) with a peri-implant infection and severe bone loss at 8 weeks was considered an early failure.


This study showed that 83% of implants reached the threshold level of ISQ ≥ 70 after 8 weeks, allowing an early loading protocol. The early failure rate was considered low with 0.9%. The RFA technology is a suitable method to objectively monitor implant stability longitudinally.


Implant Stability Quotient; SLActive; autogenous bone grafts; dental implant; deproteinized bovine bone mineral; early implant loading; resonance frequency analysis; sinus floor elevation

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