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Korean J Intern Med. 2016 Jan;31(1):54-64. doi: 10.3904/kjim.2016.31.1.54. Epub 2015 Dec 28.

Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding.

Author information

1
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
2
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.

Abstract

BACKGROUND/AIMS:

Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition.

METHODS:

A prospective observational study was conducted at a single hospital between April 2010 and November 2012, and 336 patients with symptoms and signs of gastrointestinal bleeding were consecutively enrolled. Clinical characteristics and endoscopic findings were reviewed to identify potential factors associated with 30-day mortality.

RESULTS:

Overall, 184 patients were included in the study (men, 79.3%; mean age, 59.81 years), and 16 patients died within 30 days (8.7%). Multivariate analyses revealed that comorbidity of diabetes mellitus (DM) or metastatic malignancy, age ≥ 65 years, and hypotension (systolic pressure < 90 mmHg) during hospitalization were significant predictive factors of 30-day mortality.

CONCLUSIONS:

Comorbidity of DM or metastatic malignancy, age ≥ 65 years, and hemodynamic instability during hospitalization were predictors of 30-day mortality in patients with NVUGIB. These results will help guide the management of patients with this condition.

KEYWORDS:

Comorbidity; Gastrointestinal hemorrhage; Mortality; Prognosis

PMID:
26767858
PMCID:
PMC4712435
DOI:
10.3904/kjim.2016.31.1.54
[Indexed for MEDLINE]
Free PMC Article

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