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FEMS Microbiol Lett. 1989 Jul 1;51(1):85-8.

The barrier function of the outer membrane of Pseudomonas maltophilia in the diffusion of saccharides and beta-lactam antibiotics.

Author information

1
Department of Cellular Information Sciences, Tokai University School of Medicine, Isehara, Japan.

Abstract

This paper reports that the efficiency of solute diffusion through the outer membrane of Pseudomonas maltophilia is roughly 3 to 5% of that of Escherichia coli. This is despite the fact that the outer membrane pore(s) is only a little smaller than that of E. coli. These results suggest that P. maltophilia has a low copy number of porin(s). The outer membrane of antibiotic resistant clinical isolates showed even less efficient permeability towards saccharides and antibiotics than the laboratory strains.

PMID:
2676712
DOI:
10.1016/0378-1097(89)90082-7
[Indexed for MEDLINE]

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