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Expert Rev Clin Immunol. 2016;12(5):551-61. doi: 10.1586/1744666X.2016.1142373. Epub 2016 Feb 29.

Pre-Emptive Avoidance Strategy (P.E.A.S.) - addressing allergic contact dermatitis in pediatric populations.

Author information

1
a School of medicine , Loma Linda University , Loma Linda , CA , USA.
2
b Preliminary Internal Medicine and Dermatology , San Diego Medical Center, University of California , La Jolla , CA , USA.
3
c Pediatric Dermatology Clinic , Loma Linda University , Loma Linda , CA , USA.
4
d Dermatology Resident , Eastern Virginia Medical School , Norfolk , VA , USA.
5
e Dermatology , Children's Specialty Clinic , Norfolk , VA , USA.
6
f Pediatrics and Dermatology , Eastern Virginia Medical School , Norfolk , VA , USA.
7
g Contact Dermatitis Clinic , Loma Linda University , Loma Linda , CA , USA.

Abstract

Pediatric allergic contact dermatitis (ACD) has been increasingly recognized in the United States. Reported rates of positive patch tests in children referred for suspected ACD range between 27 and 95.6%. Many young children are becoming sensitized to contact allergens found in personal hygiene products. We reviewed five recent pediatric patch test studies to determine the top allergens associated with this source of ACD in children. The top ten allergens were neomycin, balsam of Peru, fragrance mix, lanolin, cocamidopropylbetaine, formaldehyde, corticosteroids, methylchlorisothiazolinone (MCI)/methylisothiazolinone (MI), propylene glycol, and benzalkonium chloride. We estimate that one third of children suffering from ACD could potentially benefit from a 'pre-emptive avoidance strategy' (P.E.A.S.) of the stated top 10 allergens.

KEYWORDS:

Allergy; allergen; contact dermatitis; dermatitis; pediatric; pre-emptive avoidance strategy

PMID:
26764601
DOI:
10.1586/1744666X.2016.1142373
[Indexed for MEDLINE]

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