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Pituitary. 2016 Aug;19(4):345-55. doi: 10.1007/s11102-015-0703-0.

Arginine vasopressin (AVP): a review of its historical perspectives, current research and multifunctional role in the hypothalamo-hypophysial system.

Author information

1
Division of Pathology, Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, Toronto, ON, M5B 1T8, Canada. rotondof@smh.ca.
2
Division of Pathology, Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, Toronto, ON, M5B 1T8, Canada.
3
Department of Neurosurgery, Hospital Pablo Tobon Uribe and Clinica Medellin, Medellín, Colombia.
4
Department of Neurosurgery, Macquarie University Hospital, Sydney, Australia.
5
Division of Endocrinology, Clinica Medellin, Medellín, Colombia.
6
Departamento de Fisiología y Farmacología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
7
Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

Abstract

INTRODUCTION:

This publication reviews the function of arginine vasopressin and focuses on the morphologic and functional correlation between the hormone and its effect on stress, the hypophysial-adrenocortical axis, neuroimmune responses, renal function and corticotroph pituitary tumors.

MATERIALS AND METHODS:

A literature review was performed using various search engines for information regarding the morphology and the multifunctional role of arginine vasopressin.

RESULTS:

Although a large number of studies were published discussing these interactions, there are several important areas that are still obscure.

CONCLUSION:

The questions of how does arginine vasopressin affect the morphology and function of these various areas, and how does the secretion of ACTH and adrenocortical hormones influence the morphology of arginine vasopressin-producing cells and their hormone secretion requires further investigation.

KEYWORDS:

Arginine vasopressin; Corticotroph cells; Hypothalamus; Pituitary; Receptors

PMID:
26762848
DOI:
10.1007/s11102-015-0703-0
[Indexed for MEDLINE]

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