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Horm Res Paediatr. 2016;85(2):125-30. doi: 10.1159/000443236. Epub 2016 Jan 13.

Birth Weight Could Influence Bone Mineral Contents of 10- to 18-Year-Old Korean Adolescents: Results from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010.

Author information

1
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Abstract

BACKGROUND:

We investigate the relationship between birth weight (BW) and bone mineral content (BMC) in Korean adolescents.

METHODS:

Data were obtained from the Korea National Health and Nutrition Examination Survey conducted in 2010. Baseline characteristics were compared according to age- and sex-specific BMC quartiles of total body less head (TBLH), lumbar spine (LS) and femur neck (FN) in 10- to 18-year-old adolescents (male = 474, female = 394).

RESULTS:

BW showed a positive correlation with current weight-SDS (p = 0.006 in males, p = 0.008 in females). BW according to TBLH-BMC quartile groups (p for trend <0.003 in males, <0.0001 in females), LS-BMC quartile groups (p for trend <0.034 in males) and FN-BMC quartile groups (p for trend <0.008 in males, <0.020 in females) showed significant differences. The odds ratio (OR) of being in the highest BMC quartile, per 1-kg increase in BW, was significantly increased in TBLH-BMC (OR = 2.14 in males, OR = 3.26 in >16-year-old adolescents) and FN-BMC (OR = 2.62 in males, OR = 3.06 in >16-year-old adolescents) after adjusting for age, height, smoking, drinking, metabolic equivalent of task, and gestational age.

CONCLUSION:

BW might be one of the determinant factors of BMC in Korean adolescents.

PMID:
26756382
DOI:
10.1159/000443236
[Indexed for MEDLINE]

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