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J Cell Biol. 2016 Jan 18;212(2):135-7. doi: 10.1083/jcb.201512086. Epub 2016 Jan 11.

My oh my(osin): Insights into how auditory hair cells count, measure, and shape.

Author information

1
Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106.
2
Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 Department of Biology, Case Western Reserve University, Cleveland, OH 44106.
3
Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 Department of Biology, Case Western Reserve University, Cleveland, OH 44106 Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 bmm30@case.edu.

Abstract

The mechanisms underlying mechanosensory hair bundle formation in auditory sensory cells are largely mysterious. In this issue, Lelli et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201509017) reveal that a pair of molecular motors, myosin IIIa and myosin IIIb, is involved in the hair bundle's morphology and hearing.

PMID:
26754648
PMCID:
PMC4721532
DOI:
10.1083/jcb.201512086
[Indexed for MEDLINE]
Free PMC Article

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