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Crit Rev Food Sci Nutr. 2017 Oct 13;57(15):3332-3343. doi: 10.1080/10408398.2015.1117413.

Association between vitamin deficiency and metabolic disorders related to obesity.

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a Escuela de Nutrición y Dietética, Facultad de Ciencias de la Salud , Universidad de Talca , Talca , Chile.
b Center of Agrarian Sciences , Universidade Federal do Espírito Santo , Alegre , Espírito Santo , Brazil.
c Department of Nutrition and Health , Universidade Federal de Viçosa , Viçosa , Minas Gerais , Brazil.


Inappropriate food behavior contributes to obesity and leads to vitamin deficiency. This review discusses the nutritional status of water- and fat-soluble vitamins in obese subjects. We verified that most vitamins are deficient in obese individuals, especially the fat-soluble vitamins, folic acid, vitamin B12 and vitamin C. However, some vitamins have been less evaluated in cases of obesity. The adipose tissue is considered a metabolic and endocrine organ, which in excess leads to changes in body homeostasis, as well as vitamin deficiency which can aggravate the pathological state. Therefore, the evaluation of vitamin status is of fundamental importance in obese individuals.


Obesity; fat-soluble vitamins; metabolic disorders; vitamin deficiency; water-soluble vitamins

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