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Vet Res Commun. 2016 Mar;40(1):29-38. doi: 10.1007/s11259-015-9651-4. Epub 2016 Jan 7.

Clinical evaluation of an antiinflammatory and antioxidant diet effect in 30 dogs affected by chronic otitis externa: preliminary results.

Author information

1
School of Specialization in Clinical Biochemistry, "G. d'Annunzio" University, Chieti, Italy. alessandro811@hotmail.it.
2
Research and Development Department, SANYpet S.p.a., Bagnoli di Sopra, Padua, Italy. Sarac.sanypet@forza10.com.
3
School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy. francesca.beribe@unicam.it.
4
School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy. fulvio.laus@unicam.it.
5
School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy. matteo.cerquetella@unicam.it.
6
School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy. andrea.spaterna@unicam.it.
7
Research and Development Department, SANYpet S.p.a., Bagnoli di Sopra, Padua, Italy. Gianandrea.sanypet@forza10.com.
8
Research and Development Department, SANYpet S.p.a., Bagnoli di Sopra, Padua, Italy. Sergio.sanypet@forza10.com.
9
Department of Science, University of Basilicata, Potenza, Italy. giuseppe.terrazzano@unibas.it.
10
Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy. giuseppe.terrazzano@unibas.it.

Abstract

The aim of this evaluation study was to assess the possible role of a specific nutraceutical diet in relieving main clinical symptoms of chronic bilateral otitis externa (occlusion of ear canal, erythema, discharge quantity, and odor) in 30 adult dogs. Thirty dogs of different breeds (mean age ± SEM; 6.03 ± 0.15 years and mean weight ± SEM; 32.01 ± 1.17 Kg; 53.3% males, 46.6% females) with evident chronic clinical otitis symptoms were equally divided and randomly assigned to receive either the nutraceutical diet (ND group) or a standard diet (SD group) over a period of 90 days. In all cases a topical pharmacological treatment was given. The nutraceutical diet, also endowed with anti-inflammatory and antioxidant activities, significantly decreased the mean score intensity of all symptoms after 90 days of intervention (P < 0.0001) with the exception of Malassezia pachydermatis infection which was only slightly reduced. Our investigation is one of the few evidence-based results where a commercial nutraceutical diet has been proven effective, in combination with drugs, in relieving otitis externa-related symptoms. This study opens new insights into otitis externa clinical management providing evidence of efficacy of a combined therapy with drugs and a specific nutraceutical diet.

KEYWORDS:

Antiinflammatory and antioxidant activities; Nutraceutical diet; Otitis externa; Symptoms intensity decrease

PMID:
26743397
PMCID:
PMC4754334
DOI:
10.1007/s11259-015-9651-4
[Indexed for MEDLINE]
Free PMC Article

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