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Clin Med Insights Reprod Health. 2015 Dec 22;9:39-43. doi: 10.4137/CMRH.S25056. eCollection 2015.

Cryptorchidism and Fertility.

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Resident, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Student, Faculty of Medicine, Cairo University, Cairo, Egypt.
Resident, Faculty of Medicine, October 6 University, Giza, Egypt.
Professor of Urology, Faculty of Medicine, Cairo University, Cairo, Egypt.


Cryptorchidism, the failure of one or both testes to descend into the scrotum prenatally, occurs in 2.4%-5% of newborns. Many of these testes will descend spontaneously shortly after birth, but ~23% will remain undescended unless surgery is performed. Bilaterally cryptorchid men have a six times greater risk of being infertile when compared with unilaterally cryptorchid men and the general male population. Approximately 10% of infertile men have a history of cryptorchidism and orchidopexy. The main reasons for infertility in men with a history of cryptorchidism treated by orchidopexy are maldevelopment of the testes and an improper environment for the normal development of the testes, hyperthermia, and antisperm antibodies.


cryptorchidism; fertility; orchidopexy; undescended testis

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