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Br J Psychiatry. 1989 Feb;154:147-69.

The Gilles de la Tourette syndrome: the current status.

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Academic Department of Psychiatry, University College, Middlesex Hospital, London.


The Gilles de la Tourette Syndrome is a movement disorder characterised by both motor and vocal (phonic) tics. It was once thought to be rare, and the literature until the 1970s consisted predominantly of case reports, both highlighting the fascinating clinical manifestations and speculating as to their aetiology. Many areas of GTS are under investigation, including the neurology, psychopathology, neurophysiology, biochemistry, and genetics. This review briefly considers early descriptions of GTS as well as current research, highlighting the areas of agreement and controversy.

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