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J Child Neurol. 2016 Oct;31(12):1412-20. doi: 10.1177/0883073815620673. Epub 2015 Dec 29.

Neurological Complications of Pediatric Cancer.

Author information

1
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
2
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
3
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA Department of Pediatrics, Weill Medical College of Cornell University, New York, NY, USA KhakooY@mskcc.org.

Abstract

Neurologists are often consulted for diagnosis and management of neurologic complications in patients undergoing therapy for cancer. Pediatric patients with cancer, often undergoing the same types of therapy as adults with cancer, may experience different adverse events. The set of neurologic complications in children differs from that in adults and the neurologist must take into account the continuing growth and development of the patient as well as significant differences in primary diagnosis across the population. Correctly recognizing complications and initiating prompt treatment may reduce pain and prevent further progression and permanent deficits. Herein, we review the most recent literature on the neurological complications of cancer therapy organized by frequency in the pediatric population.

KEYWORDS:

headaches; neurologic sequelae; pediatric oncology; seizures; toxicities

PMID:
26719497
PMCID:
PMC4927408
DOI:
10.1177/0883073815620673
[Indexed for MEDLINE]
Free PMC Article

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