Nuclear Image-Guided Approaches for Cardiac Resynchronization Therapy (CRT)

Curr Cardiol Rep. 2016 Jan;18(1):7. doi: 10.1007/s11886-015-0687-4.

Abstract

Cardiac resynchronization therapy (CRT) is a standard treatment for patients with heart failure. However, 30-40 % of the patients having CRT do not respond to CRT with improved clinical symptom and cardiac functions. It is important for CRT response that left ventricular (LV) lead is placed away from scar and at or near the site of the latest mechanical activation. Nuclear image-guided approaches for CRT have shown significant clinical value to assess LV myocardial viability and mechanical dyssynchrony, recommend the optimal LV lead position, and navigate the LV lead to the target coronary venous site. All these techniques, once validated and implemented, should impact the current clinical practice.

Keywords: Cardiac resynchronization therapy (CRT); Heart failure (HF); Left ventricle (LV); Mechanical dyssynchrony.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cardiac Resynchronization Therapy / methods*
  • Cardiac Resynchronization Therapy / mortality
  • Cardiac Resynchronization Therapy Devices
  • Heart Failure / diagnostic imaging*
  • Heart Failure / physiopathology
  • Heart Failure / therapy
  • Heart Ventricles / diagnostic imaging*
  • Heart Ventricles / physiopathology
  • Humans
  • Patient Selection
  • Practice Guidelines as Topic
  • Surgery, Computer-Assisted
  • Tomography, Emission-Computed, Single-Photon*
  • Treatment Outcome
  • Ultrasonography, Interventional*
  • Ventricular Function, Left