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Ann Indian Acad Neurol. 2015 Oct-Dec;18(4):424-9. doi: 10.4103/0972-2327.165469.

Clinicoanatomical correlation in stroke related aphasia.

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Department of Neurology, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.
Department of Audiology and Speech Therapy, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.



With advances in neuroimaging, traditional views regarding the clinicoanatomic correlation in stroke patients with aphasia are being challenged and it has been observed that lesions at a given cortical or subcortical site may manifest with different aphasia profiles.


To study as to whether there is a strict clinicoanatomical correlation between the type of aphasia and lesion site in patients with first ever stroke.


Observational study, based in a tertiary care center.


Stroke patient's ≥18 years of age were screened and those with first ever stroke and aphasia were subjected to a detailed stroke workup and language assessment using the Hindi version of Western Aphasia Battery (WAB). Statistical analysis was done with χ(2) test with Yates correction and Kruskal-Wallis test. The level of significance was set at P < 0.05.


Overall aphasia was detected in 27.9% of the 260 screened cases with stroke. Amongst 60 cases with first ever stroke and aphasia, the aphasia type was: Global (33.33%), Broca's (28.3%), transcortical motor (13.33%), transcortical sensory (10%), Wernicke's (8.33%), anomic (5%), and conduction (1.67%) aphasia. A definite correlation between the lesion site and the type of aphasia as per the traditional classification was observed in 35% cases only.


No absolute correlation exists between the lesion site and the type of clinical aphasia syndrome in majority of the patients with cortical and subcortical stroke.


Aphasia; clinico-anatomic correlation; clinico-topographic correlation; stroke

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