Format

Send to

Choose Destination
Trends Neurosci. 2016 Jan;39(1):1-2. doi: 10.1016/j.tins.2015.12.001. Epub 2015 Dec 17.

A Spinal Circuit for Mechanically-Evoked Itch.

Author information

1
Pain Research Center, Department of Anesthesiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: steve.davidson@uc.edu.

Abstract

A satisfactory neurobiological understanding of itch has proved difficult to reach. Bourane et al. have now uncovered a previously unrecognized spinal circuit for mechanically-induced itch and elucidated a mechanism that keeps it in check. Dysregulation of this circuit could contribute to chronic itch, suggesting a new strategy for itch relief.

KEYWORDS:

Itch; mechanoreceptor; pain; scratch; spinal; touch

PMID:
26708015
DOI:
10.1016/j.tins.2015.12.001
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center