Format

Send to

Choose Destination
Curr Treat Options Neurol. 2016 Jan;18(1):1. doi: 10.1007/s11940-015-0385-y.

Use of Cannabinoids for Spasticity and Pain Management in MS.

Author information

1
Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, 304 A, San Francisco, CA, 94117, USA. Hardeep.Chohan@ucsf.edu.
2
Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, 304 A, San Francisco, CA, 94117, USA.
3
Department of Neurology, Oregon Health and Science University, Portland, OR, USA.

Abstract

Several randomized trials have demonstrated potential benefit of cannabis derivatives in the symptomatic treatment of multiple sclerosis (MS) patients. These provide class 1 and 2 evidence for cannabinoid product use for spasticity and pain in these patients. The precise best ratio or doses are not yet clear. The safety and potential long-term effects of these products on cognitive function in people with MS have not been evaluated. Since short-term memory and processing speed can be significantly impaired in many people with MS, the concern of potential cognitive impairment related to cannabis products needs consideration in clinical care and should be addressed in longer, prospective studies.

KEYWORDS:

Cannabidiol; Cannabinoids; Multiple sclerosis; Pain; Spasticity; Tetrahydrocannabinol

PMID:
26705757
DOI:
10.1007/s11940-015-0385-y

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center