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J Pediatr Psychol. 2016 Apr;41(3):277-86. doi: 10.1093/jpepsy/jsv117. Epub 2015 Dec 22.

Marijuana Use and Psychiatric Disorders in Perinatally HIV-Exposed Youth: Does HIV Matter?

Author information

1
HIV Center for Clinical and Behavioral Studies, Columbia University and New York State Psychiatric Institute, ke2143@cumc.columbia.edu.
2
Special Needs Clinic, New York Presbyterian Hospital and Columbia University Medical Center, and.
3
HIV Center for Clinical and Behavioral Studies, Columbia University and New York State Psychiatric Institute.
4
Department of Behavioral and Social Sciences, Brown University.

Abstract

OBJECTIVE:

 To examine longitudinal reciprocal relationships between marijuana use and psychiatric disorders, and identify the role of HIV in a sample (N = 340) of youth perinatally infected with HIV (PHIV+) and youth perinatally exposed but uninfected with HIV (PHIV-) (60.6% PHIV+; 9-16 years at baseline; 51% female). 

METHODS:

 Cross-lagged structural equation modeling was used to examine longitudinal associations between changes in marijuana use and changes in any behavioral, mood, and anxiety disorders at three time points across adolescence. 

RESULTS:

 Marijuana use predicted behavioral and mood disorders in youth, regardless of HIV status. Behavioral and mood disorders predicted marijuana use for PHIV- youth; behavioral disorders predicted marijuana use for PHIV+ youth. Anxiety disorders and marijuana use were not associated for either group. 

CONCLUSIONS:

 For PHIV+ and PHIV- youth, interventions that target early marijuana use may reduce later psychiatric disorders. Similarly, treatment for early behavioral disorders may prevent subsequent marijuana use.

KEYWORDS:

adolescent HIV; longitudinal; marijuana use; perinatal HIV; psychiatric disorders

PMID:
26698841
PMCID:
PMC5013838
DOI:
10.1093/jpepsy/jsv117
[Indexed for MEDLINE]
Free PMC Article

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