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Asian J Androl. 2016 Mar-Apr;18(2):213-6. doi: 10.4103/1008-682X.169560.

When is a varicocele repair indicated: the dilemma of hypogonadism and erectile dysfunction?

Author information

1
Department of Male Reproductive Medicine, Weill Cornell Medical College, New York, USA.

Abstract

In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain. The surgical treatment of varicocele for hypogonadism is controversial and debated. Recently, multiple reports in the literature have suggested that varicocele is associated with hypogonadism and varicocele repair can increase testosterone levels. Men with hypogonadal symptoms should have at least two serum testosterone levels. Microsurgical varicocelectomy may be beneficial for men with clinically palpable varicoceles with documented hypogonadism. In this review, we summarize the most recent literature linking varicocele to hypogonadism and sexual dysfunction and the impact of repair on serum testosterone levels. We performed a search of the published English literature. The key words used were "varicocele and hypogonadism" and "varicocele surgery and testosterone." We included published studies after 1998. We, also, evaluated the effect of surgery on the changes in the serum testosterone level regardless of the indication for the varicocele repair.

PMID:
26696437
PMCID:
PMC4770488
DOI:
10.4103/1008-682X.169560
[Indexed for MEDLINE]
Free PMC Article

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