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J Cutan Pathol. 2016 Apr;43(4):400-5. doi: 10.1111/cup.12661. Epub 2016 Feb 11.

Primary cutaneous CD30+ anaplastic large cell lymphoma treated with radiotherapy and methotrexate with development of xanthomas at the sites of prior disease.

Author information

1
Department of Dermatology, Ramón y Cajal University Hospital, Madrid, Spain.
2
Department of Pathology, Ramón y Cajal University Hospital, Madrid, Spain.

Abstract

Primary cutaneous anaplastic large cell lymphoma is a rare type of cutaneous T-cell lymphoma, and the involvement of the ocular adnexa is extremely rare. Secondary xanthoma-like changes after radiation therapy or chemotherapy have been rarely reported in association with large-cell T-cell anaplastic lymphoma. We report one case of a primary C-anaplastic large cell lymphoma affecting the eyelid with fast progression with multiple nodules in various anatomic sites and development of xanthoma-like lesions after treatment.

KEYWORDS:

anaplastic large cell lymphoma; methotrexate; ocular adnexa; radiotherapy; xanthoma

PMID:
26695345
DOI:
10.1111/cup.12661
[Indexed for MEDLINE]

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