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Nat Rev Cancer. 2016 Jan;16(1):7-19. doi: 10.1038/nrc.2015.5.

NK cells and cancer: you can teach innate cells new tricks.

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  • 1Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California 94143, USA.

Abstract

Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic function that provide host defence against microbial infection and tumours. Here, we review evidence for the role of NK cells in immune surveillance against cancer and highlight new therapeutic approaches for targeting NK cells in the treatment of cancer.

PMID:
26694935
DOI:
10.1038/nrc.2015.5
[PubMed - indexed for MEDLINE]
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