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Nat Prod Rep. 2016 Feb;33(2):231-316. doi: 10.1039/c5np00125k.

Biosynthesis of polyketides by trans-AT polyketide synthases.

Author information

1
Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland. jpiel@ethz.ch.

Abstract

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides. The article includes 609 references and covers the literature from 2009 through June 2015.

PMID:
26689670
DOI:
10.1039/c5np00125k
[Indexed for MEDLINE]

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