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Mol Cell. 2015 Dec 17;60(6):832-3. doi: 10.1016/j.molcel.2015.12.006.

Nifty Alleles, a Plethora of Interactions, and Imagination Advance Understanding of Smc5/6's Roles with Chromosomes.

Author information

1
Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85721, USA.
2
Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85721, USA. Electronic address: tweinert@email.arizona.edu.

Abstract

The Smc5/6 complex is involved in DNA replication and repair, but why it is essential is less clear. In this issue of Molecular Cell, Menolfi et al. (2015) use cell cycle-specific alleles to link the essential function of Smc5/6 to resolving replication problems that persist into G2.

PMID:
26687598
DOI:
10.1016/j.molcel.2015.12.006
[Indexed for MEDLINE]
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