Format

Send to

Choose Destination
Brain Cogn. 2016 Feb;102:1-12. doi: 10.1016/j.bandc.2015.11.005. Epub 2015 Dec 9.

The effect of anodal transcranial direct current stimulation on motor sequence learning in healthy individuals: A systematic review and meta-analysis.

Author information

1
Department of Physiotherapy, School of Primary Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia. Electronic address: fahimeh.hashemirad@monash.edu.
2
Department of Medicine at Royal Melbourne Hospital, The University of Melbourne, Melbourne, Australia.
3
Monash Alfred Psychiatry Research Centre, The Alfred and Monash University Central Clinical School, Melbourne, Australia.
4
Department of Physiotherapy, School of Primary Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.

Abstract

A large number of studies have indicated the effect of anodal transcranial direct current stimulation (a-tDCS) on the primary motor cortex (M1) during motor skill training. The effects of a-tDCS on different stages of motor sequence learning are not yet completely understood. The purpose of this meta-analysis was to determine the effects of single and multiple sessions of a-tDCS on two different tasks: the sequential finger tapping task/serial reaction time task (SEQTAP/SRTT) and the sequential visual isometric pinch task (SVIPT). We searched electronic databases for M1 a-tDCS studies. Thirteen studies met the inclusion criteria. The results indicate that application of multiple sessions of a-tDCS, compared to single session a-tDCS induced a significant improvement in skill in both SEQTAP/SRTT and SVIPT. Retention after a single day and multiple days of a-tDCS was statistically significant for the SEQTAP/SRTT task but not for SVIPT. Therefore, our findings suggest that application of M1 a-tDCS across the three or five consecutive days can be helpful to improve motor sequence learning.

KEYWORDS:

Corticospinal excitability; Motor sequence learning; Primary motor cortex; Transcranial direct current stimulation (tDCS)

PMID:
26685088
DOI:
10.1016/j.bandc.2015.11.005
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center