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Int J Immunopathol Pharmacol. 2016 Jun;29(2):267-73. doi: 10.1177/0394632015590949. Epub 2015 Dec 18.

Evaluation of an oral appliance in patients with mild to moderate obstructive sleep apnea syndrome intolerant to continuous positive airway pressure use: Preliminary results.

Author information

1
Department of Basic Medical Science, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
2
Department of Basic Medical Science, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy andrea.ballini@me.com.
3
Department of Morphologic and Surgical Sciences, Insubria University, Varese, Italy.
4
Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.
5
Department of Biomedical, Surgical and Dental Sciences, Unit of Orthodontics and Paediatric Dentistry, University of Milan, Milan, Italy.

Abstract

Obstructive sleep apnea syndrome (OSAS) is a phenomenon of repeated, episodic reduction, or cessation of airflow (hypopnea/apnea) as a result of upper airways obstruction. First-line treatment in younger children is adenotonsillectomy, although other available treatment options in middle-aged adults include continuous positive airways pressure (CPAP) and airway adjuncts. Oral appliances (OA) are a viable treatment alternative in patients with OSAS.The objective of this study was to assess, in a 1-year follow-up study, an OA in OSAS patients. The participants were subjected to polysomnographic examination with a validated device (MicroMESAM). Eight participants were fitted with a Thornton Adjustable Positioner (TAP). The participants were asked to wear the test appliance for 7 nights, and in case of compliance, for 6 months. The selected patients record their usage of the appliance and any adverse effects in a treatment journal. The research focused on the following outcomes: sleep apnea (i.e. reduction in the apnea/hypopnea index) and the effect of oral appliances on daytime function.In conclusion, the results suggest that OA have a definite role in the treatment of snoring and sleep apnea.

KEYWORDS:

Thornton Adjustable Positioner; apnea-hypopnea index; continuous positive airway pressure; obstructive sleep apnea syndrome; oral appliance

PMID:
26684627
PMCID:
PMC5806714
DOI:
10.1177/0394632015590949
[Indexed for MEDLINE]
Free PMC Article

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