Format

Send to

Choose Destination
Lancet Oncol. 2015 Dec;16(16):e595-603. doi: 10.1016/S1470-2045(15)00166-7.

Response assessment after stereotactic body radiotherapy for spinal metastasis: a report from the SPIne response assessment in Neuro-Oncology (SPINO) group.

Author information

1
Department of Radiation Oncology, Centre Hospitalier Universitaire de Quebec, Université Laval, Quebec City, QC, Canada.
2
Department of Radiation Oncology, University of Southern California, Los Angeles, CA, USA.
3
Department of Neurosurgery, University of Virginia Health System, Charlottesville, VA, USA.
4
Department of Medical Oncology, Cleveland Clinic, Cleveland, OH, USA.
5
Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland; Department of Radiation Oncology, University Hospital Wuerzburg, Wuerzberg, Germany.
6
Department of Neurosurgery, Inje University Ilsan Paik Hospital, Goyang, Korea.
7
Department of Radiation Oncology, Stony Brook University, New York, NY, USA.
8
Department of Radiation Oncology, Princess Alexandra Hospital, Brisbane, QLD, Australia.
9
Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Cleveland, OH, USA.
10
Department of Neurosurgery, University of Munich Hospital, Munich, Germany.
11
Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA, USA.
12
Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
13
Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
14
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
15
Department of Radiology, University Health Network, Toronto, ON, Canada.
16
Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
17
Department of Orthopedics, University of British Columbia, Vancouver, BC, Canada.
18
Division of Neuro-Oncology, University of Virginia Health System, Charlottesville, VA, USA.
19
Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.
20
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
21
Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
22
Department of Radiation Oncology, University of Toronto, Sunnybrook Odette Cancer Centre, Toronto, ON, Canada.
23
NCIC Clinical Trials Group Division, Cancer Research Institute, Queen's University Kingston, ON, Canada.
24
Brain Tumor and Neuro-Oncology Center and Department of Neurosurgery, Cleveland Clinic, Cleveland, OH, USA.
25
Department of Radiation Oncology, University of Toronto, Sunnybrook Odette Cancer Centre, Toronto, ON, Canada. Electronic address: arjun.sahgal@sunnybrook.ca.

Abstract

The SPine response assessment In Neuro-Oncology (SPINO) group is a committee of the Response Assessment in Neuro-Oncology working group and comprises a panel of international experts in spine stereotactic body radiotherapy (SBRT). Here, we present the group's first report on the challenges in standardising imaging-based assessment of local control and pain for spinal metastases. We review current imaging modalities used in SBRT treatment planning and tumour assessment and review the criteria for pain and local control in registered clinical trials specific to spine SBRT. We summarise the results of an international survey of the panel to establish the range of current practices in assessing tumour response to spine SBRT. The ultimate goal of the SPINO group is to report consensus criteria for tumour imaging, clinical assessment, and symptom-based response criteria to help standardise future clinical trials.

PMID:
26678212
DOI:
10.1016/S1470-2045(15)00166-7
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center