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ACS Appl Mater Interfaces. 2016 Jan 13;8(1):1-5. doi: 10.1021/acsami.5b09079. Epub 2015 Dec 22.

A Rapid Colorimetric Sensor of Clenbuterol Based on Cysteamine-Modified Gold Nanoparticles.

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Faculty of Science, Ningbo University , Ningbo 315211, China.
Key Laboratory of Magnetic Materials and Devices, and Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering , Ningbo 315201, China.


Demonstrated was a simple visual and rapid colorimetric sensor for detection of clenbuterol (CLB) based on gold nanoparticles (AuNPs) modified with cysteamine (CA) and characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), UV-vis. The solution color from red to blue gray with increasing clenbuterol concentration resulted from the aggregation of AuNPs. The detection limit of clenbuterol is 50 nM by naked eyes. The selectivity of CA-AuNPs detection system for clenbuterol is excellent compared with other interferents in food. This sensor has been successfully applied to detect clenbuterol in real blood sample.


clenbuterol; colorimetric detection; excellent selectivity; gold nanoparticle; high sensitivity

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