Inheritance patterns in recurrent aphthous ulcers: twin and pedigree data

Oral Surg Oral Med Oral Pathol. 1977 Jun;43(6):886-91. doi: 10.1016/0030-4220(77)90081-0.

Abstract

Nineteen sets of twins and 318 individuals from six families were examined and interviewed in order to ascertain whether a genetic component could be established for recurrent aphthous ulcers (RAU). While no specific mode of inheritance could be established, the data strongly support the hypothesis of a genetic factor involved in susceptibility to the disease.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Diseases in Twins*
  • Female
  • Heterozygote
  • Homozygote
  • Humans
  • Pedigree
  • Pregnancy
  • Recurrence
  • Stomatitis, Aphthous / genetics*
  • Twins, Dizygotic
  • Twins, Monozygotic