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Physiology (Bethesda). 2016 Jan;31(1):25-33. doi: 10.1152/physiol.00039.2015.

Novel Functions of Renin Precursors in Homeostasis and Disease.

Author information

1
University of Virginia School of Medicine, Child Health Research Center, Charlottesville, Virginia rg@virginia.edu msl7u@virginia.edu.

Abstract

Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis, renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses. In the bone marrow, renin cells offer clues to understand normal and neoplastic hematopoiesis.

PMID:
26661526
PMCID:
PMC4698453
DOI:
10.1152/physiol.00039.2015
[Indexed for MEDLINE]
Free PMC Article

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