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Clin Pharmacol Ther. 2016 Mar;99(3):262-5. doi: 10.1002/cpt.316. Epub 2016 Jan 17.

Improving therapeutic effectiveness and safety through big healthcare data.

Author information

1
Division of Pharmacoepidemiology, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Abstract

Big healthcare data-electronically recorded longitudinal data generated during the provision and administration of healthcare for millions of patients-have become essential for understanding the effectiveness and safety of therapeutics. They are most effectively used in concert with experimental and laboratory research throughout the life cycle of a drug. Applications range from providing phenotype and health outcomes information in genome-wide association studies to postmarketing studies that assure prescribers of the safety of approved drugs (Figure ). [Figure: see text].

PMID:
26659268
DOI:
10.1002/cpt.316
[Indexed for MEDLINE]

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