Determination of impurities in (124)I samples by high resolution gamma spectrometry

M C M de Almeida; R L da Silva; J U Delgado; R Poledna; M T F de Araújo; A S Laranjeira; E de Veras; A M S Braghirolli; G R Dos Santos; R T Lopes

doi:10.1016/j.apradiso.2015.11.060

Determination of impurities in (124)I samples by high resolution gamma spectrometry

Appl Radiat Isot. 2016 Mar:109:261-263. doi: 10.1016/j.apradiso.2015.11.060. Epub 2015 Nov 25.

Authors

Affiliations

¹ LNMRI, IRD, Comissão Nacional de Energia Nuclear, Av Salvador Allende, S/N, RJ CEP 22783-127, Brazil. Electronic address: marcandida@yahoo.com.br.
² Instituto de Radioproteção e Dosimetria, RJ, Brazil.
³ Instituto de Radioproteção e Dosimetria, RJ, Brazil; Laboratório de Instrumentação Nuclear (LIN/PEN/COPPE/UFRJ), Caixa Postal 68509, CEP 21945-970 RJ, Brazil.
⁴ Instituto de Engenharia Nuclear, RJ, Brazil.
⁵ Laboratório de Instrumentação Nuclear (LIN/PEN/COPPE/UFRJ), Caixa Postal 68509, CEP 21945-970 RJ, Brazil.

PMID: 26653211
DOI: 10.1016/j.apradiso.2015.11.060

Abstract

(124)I is a radionuclide used in the diagnosis of tumors. The National Health Agency requires identification and activity measurement of impurities. Using gamma spectrometry with an efficiency calibrated high-purity germanium detector, impurities (125)I and (126)I in an (1)(24)I production sample were identified. Activity ratios of (125)I and (126)I to (124)I were approximately 0.5% and 98%, respectively.

Keywords: (124)I; Gamma-ray spectrometry; Impurities determination.

Published by Elsevier Ltd.

MeSH terms

Brazil
Drug Contamination / prevention & control*
Iodine Radioisotopes / analysis*
Iodine Radioisotopes / standards*
Radiometry / methods*
Radiometry / standards*
Reproducibility of Results
Sensitivity and Specificity
Spectrometry, Gamma / methods
Spectrometry, Gamma / standards*

Substances

Iodine Radioisotopes