Format

Send to

Choose Destination
Diagn Microbiol Infect Dis. 2016 Feb;84(2):159-64. doi: 10.1016/j.diagmicrobio.2015.10.023. Epub 2015 Nov 11.

Clinical and economic impact of antimicrobial stewardship interventions with the FilmArray blood culture identification panel.

Author information

1
Department of Pharmacy, UF Health Shands Hospital, 1600 SW Archer Road, Gainesville, FL 32608, USA. Electronic address: joseph.pardo@va.gov.
2
Department of Pharmacy, UF Health Shands Hospital, 1600 SW Archer Road, Gainesville, FL 32608, USA.
3
Department of Pathology, Immunology and Laboratory Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32603, USA.
4
UF Health Shands Hospital Clinical Microbiology Laboratory, 1600 SW Archer Road, Gainesville, FL 32608, USA.

Abstract

The purpose of this study was to evaluate the impact of the FilmArray Blood Culture Identification (BCID) Panel on the management of patients with blood cultures growing gram positive cocci and Candida. We retrospectively compared clinical and economic outcomes between patients during the BCID testing period and a matched historical control group before BCID testing was introduced. A total of 84 BCID patients were matched to 252 historical controls. BCID identification of coagulase negative staphylococci contaminants resulted in shorter post-culture length of stay (P < 0.008) and saved roughly $30,000 per 100 patients tested. The BCID led to shorter duration of empirical vancomycin for patients with contaminated blood cultures (P = 0.005) and methicillin-susceptible Staphylococcus aureus bacteremia (P < 0.001). Patients with vancomycin-resistant enterococcal bacteremia received active therapy earlier than historical controls (P = 0.047). The BCID, coupled with antimicrobial stewardship intervention, was a cost effective tool to improve patient care.

KEYWORDS:

Antimicrobial stewardship; Bloodstream infection; Molecular diagnostics

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center