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Cell. 2015 Dec 3;163(6):1312-3. doi: 10.1016/j.cell.2015.11.040.

Genome Sequencing Fishes out Longevity Genes.

Author information

1
Department of Molecular Biology & LSI Genomics, Princeton University, Princeton NJ 08544, USA.
2
Department of Molecular Biology & LSI Genomics, Princeton University, Princeton NJ 08544, USA. Electronic address: ctmurphy@princeton.edu.

Abstract

Understanding the molecular basis underlying aging is critical if we are to fully understand how and why we age-and possibly how to delay the aging process. Up until now, most longevity pathways were discovered in invertebrates because of their short lifespans and availability of genetic tools. Now, Reichwald et al. and Valenzano et al. independently provide a reference genome for the short-lived African turquoise killifish, establishing its role as a vertebrate system for aging research.

PMID:
26638067
DOI:
10.1016/j.cell.2015.11.040
[Indexed for MEDLINE]
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