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Fortschr Med. 1989 Jun 10;107(17):385-9.

[Comparison of the action of 2 effective analgesics. Experimental study: tramadol versus tilidine/naloxone].

[Article in German]


In the present study involving healthy test subjects, tilidin/naloxone (Valoron N; VAL) proved to have an analgesic effect roughly twice as pronounced as that of tramadol (TRA). Moreover, the analgesic effect of VAL showed a significantly more rapid onset than did that of TRA. This finding reflects the difference in rate of action of the active substances. In accordance with these findings, VAL is thus the most powerful analgesic presently available on the German market on simple prescription.

[PubMed - indexed for MEDLINE]
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