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Chem Pharm Bull (Tokyo). 2015;63(12):1065-9. doi: 10.1248/cpb.c15-00465.

New Glabretal Triterpenes from the Immature Fruits of Poncirus trifoliata and Their Selective Cytotoxicity.

Author information

1
Department of Food Science and Biotechnology, Kyungnam University.

Abstract

Two new glabretal triterpenes, pancastatins A (1) and B (2), were isolated from the immature fruits of Poncirus trifoliata. Their chemical structures were elucidated by spectroscopic analyses including one- and two-dimensional NMR and high-resolution electrospray ionization mass spectrometry. Compounds 1 and 2 exhibited selective cytotoxicity against PANC-1 pancreatic cancer cells under low-glucose stress conditions.

PMID:
26633028
DOI:
10.1248/cpb.c15-00465
[Indexed for MEDLINE]
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