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Rev Esp Anestesiol Reanim. 2016 Jun-Jul;63(6):357-60. doi: 10.1016/j.redar.2015.10.004. Epub 2015 Nov 26.

Changes in haemostasis and thrombosis associated with thyroid disease: Presentation of 2 cases.

[Article in English, Spanish]

Author information

  • 1Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Complejo Hospitalario Universitario de Albacete, Albacete, España. Electronic address: ana.rodilla.fiz@gmail.com.
  • 2Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Complejo Hospitalario Universitario de Albacete, Albacete, España.

Abstract

There is a relationship between thyroid diseases and primary and secondary changes in haemostasis. The most frequent association between them are hypocoagulability states with clinical hypothyroidism and vascular thrombophilia (hypercoagulability and/or hypofibrinolysis) with hyperparathyroidism. However, there are recent studies that have detected changes in haemostasis -primary and secondary- associated with thyroid diseases with normal hormone levels, suggesting other pathogenic mechanisms not yet known. The cases are presented of 2 patients with thyroid disease that required surgery: one multinodular goitre and one papillary carcinoma of the thyroid, both with normal hormone levels. They were shown to have haemostasis disorders during the preoperative work up. These showed a Factor VII deficiency and a Factor XI deficiency along with a thrombotic disease of unknown origin, respectively.

KEYWORDS:

Coagulación; Coagulation; Thyroid; Tiroides

PMID:
26626435
DOI:
10.1016/j.redar.2015.10.004
[PubMed - in process]
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