Spontaneous sternal fracture due to multiple myeloma requiring extensive surgical repair

BMJ Case Rep. 2015 Nov 30:2015:bcr2015211498. doi: 10.1136/bcr-2015-211498.

Abstract

Spontaneous sternal fracture is a well-known complication of multiple myeloma due to osteolytic bone lesions. The possibility of a multiple myeloma should be thoroughly investigated in patients presenting with a spontaneous sternal fracture. This work up should go beyond protein electrophoresis alone as a monoclonal paraprotein is not always present. In some cases, the myeloma plasma cell clone produces only the free light chain (κ or λ) or may even be non-secretory. The underlying plasma cell dyscrasia is treated with chemotherapy and, if needed, local radiotherapy. However, for patients with a fracture causing persistent pain and physical discomfort, internal fixation may be additionally required. We present a case of a patient who presented with a displaced pathological sternal fracture. She was treated with chemotherapy, radiotherapy and an open reduction and internal fixation with a Locking Compression Plate (LCP). This technique offers a feasible option for rigid fixation of pathological fractures.

Publication types

  • Case Reports

MeSH terms

  • Bone Plates
  • Chemoradiotherapy
  • Female
  • Fracture Fixation, Internal* / methods
  • Fractures, Spontaneous / etiology*
  • Fractures, Spontaneous / surgery*
  • Humans
  • Middle Aged
  • Multiple Myeloma / complications*
  • Multiple Myeloma / diagnosis
  • Multiple Myeloma / therapy
  • Sternum / injuries*
  • Sternum / surgery*