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Chem Commun (Camb). 2016 Jan 21;52(6):1094-119. doi: 10.1039/c5cc09248e.

Fluorescent probes for the selective detection of chemical species inside mitochondria.

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Chongqing Key Laboratory of Environmental Materials and Remediation Technology, College of Materials and Chemical Engineering, Chongqing University of Arts and Sciences, 319 Honghe Avenue, Chongqing, China.
School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, China.


During the last few years, the preparation of novel fluorescent probes for the selective detection of chemical species inside mitochondria has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article focuses on the recent advances in the design principles and recognition mechanisms of these kinds of fluorescent probes. In addition, their applications for the detection of reactive oxygen species (ROS), nitric oxide, reactive sulfur species (RSS), thioredoxin (Trx), metal ions, anions, etc. in the mitochondrion is discussed as well.

[Indexed for MEDLINE]

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