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Clin Imaging. 2016 May-Jun;40(3):573-80. doi: 10.1016/j.clinimag.2015.07.027. Epub 2015 Jul 26.

What do we know about brain contrast enhancement patterns in neuromyelitis optica?

Author information

1
The Russell H. Morgan Department of Radiology and Radiological Science, Division of Neuroradiology, Johns Hopkins Hospital; Tepecik Training and Research Hospital, Department of Radiology, Izmir, Turkey. Electronic address: yelizpekcevik@yahoo.com.
2
The Russell H. Morgan Department of Radiology and Radiological Science, Division of Neuroradiology, Johns Hopkins Hospital. Electronic address: gorman1@jhmi.edu.
3
The Russell H. Morgan Department of Radiology and Radiological Science, Division of Neuroradiology, Johns Hopkins Hospital; Chungnam National University Hospital, Department of Radiology, Korea. Electronic address: leeinho1974@hanmail.net.
4
Multiple Sclerosis & Transverse Myelitis Centers, Johns Hopkins University. Electronic address: mmealy1@jhmi.edu.
5
Department of Neurology, Neuromyelitis Optica Clinic, Johns Hopkins Hospital. Electronic address: mlevy@jhmi.edu.
6
The Russell H. Morgan Department of Radiology and Radiological Science, Division of Neuroradiology, Johns Hopkins Hospital. Electronic address: iizbuda1@jhmi.edu.

Abstract

Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system that usually presents with acute myelitis and/or optic neuritis. Recently, some brain magnetic resonance imaging findings have been described in NMO that are important in the differential diagnosis. Pencil-thin, leptomeningeal, and cloud-like enhancement may be specific to NMO. These patterns are usually seen during relapses. Recognizing these lesions and enhancement patterns may expedite the diagnosis and allows early effective treatment. The purpose of this article is to review the latest knowledge and to share our experience with the contrast enhancement patterns of NMO brain lesions.

KEYWORDS:

Brain; Magnetic resonance imaging; Neuromyelitis optica; neuroimaging

PMID:
26615899
PMCID:
PMC4816659
DOI:
10.1016/j.clinimag.2015.07.027
[Indexed for MEDLINE]
Free PMC Article

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