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Urol Clin North Am. 2016 Feb;43(1):1-6. doi: 10.1016/j.ucl.2015.08.001.

The Prostate Health Index: Its Utility in Prostate Cancer Detection.

Author information

1
Department of Urology, New York University, New York, NY, USA.
2
Department of Urology, Northwestern Feinberg School of Medicine, 675 North St. Clair Street, Galter Suite 20-150, Chicago, Illinois 60611, USA.
3
Department of Urology, New York University, New York, NY, USA; Department of Population Health, Laura and Isaac Perlmutter Cancer Center, New York University, New York, NY, USA. Electronic address: stacyloeb@gmail.com.

Abstract

The Prostate Health Index is a Food and Drug Administration-approved blood test combining total, free, and [-2]pro prostate-specific antigen with greater specificity than free and total prostate-specific antigen for clinically significant prostate cancer. This article reviews the evidence on the performance of the Prostate Health Index to predict prostate biopsy outcome, its incorporation into multivariable risk-assessment tools, and its ability to predict prognosis after conservative management or prostate cancer treatment.

KEYWORDS:

Detection; Prostate Health Index; Prostate cancer; Screening

PMID:
26614024
PMCID:
PMC4663012
DOI:
10.1016/j.ucl.2015.08.001
[Indexed for MEDLINE]
Free PMC Article

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